Scientist - Protein Expression (CHO/HEK cells)

Company:  BioTalent
Location: London
Closing Date: 13/07/2024
Hours: Full Time
Type: Permanent
Job Requirements / Description
Biotalent is collaborating with a leading biotechnology company based in London focused on developing biologics to tackle cancer diseases.This is a fantastic opportunity for a scientist with strong background working with CHO/HEK cell lines within R&D. Key Responsibilities:Design and engineer plasmids for the expression of various recombinant proteins, including antibodies and antigens, in CHO/HEK cell lines.Develop stable CHO cell lines to scale up antibody production to multi-gram quantities.Optimise antibody production using fed-batch processes in bioreactors, ensuring high titer and quality.Innovate within the protein expression domain, staying abreast of and implementing cutting-edge technologies.Candidate Expectations:A solid foundation in cell and molecular biology. MSc or PhD. Proven experience in transient protein expression in CHO/HEK293 cells and in scaling up antibody production.Familiarity with bioreactor fermentation and depth filtration processes.
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